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Dr McKee compared Adams' brain to that of Aaron Hernandez, the former football star also posthumously diagnosed with CTE after he killed himself in prison at the age of 27 while serving a life sentence for a 2013 murder

In C/EBP-silenced cells, there is an accumulation of autophagic markers under oxidative stress and inflammatory conditions, indicating that C/EBP is involved in the regulation of autophagy

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Our work presents a targeted microbiome-modulation strategy that harnesses the hostpathogen microenvironment as the intervention target to limit the pathogenesis of infection, suggesting the potential for the modulation of bile salt metabolism to serve as a mechanism of action for CDI therapy