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N Engl J Med 2025

In addition, vestibular hair cells and supporting cells were absent (Rakowiecki and Epstein, 2013)

This exercise-responsive pattern led researchers to propose MOTS-c as a mitokine, a signaling molecule released by the mitochondria during physical exertion that mediates some of the systemic benefits of exercise

The GLP-1 agonist class dominates peptide drug revenue, with tirzepatide (Mounjaro/Zepbound) rapidly gaining market share as a dual-agonist alternative
