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160,161 Furthermore, A can function as a DAMP and activate the inflammasome via the TLR pathway, leading to the production of inflammatory cytokines such as IL-1

Immunomodulatory and clinical effects of receptor-interacting protein kinase 1 (RIPK1) inhibitor eclitasertib (SAR443122) in patients with severe COVID-19: a phase 1b, randomized, double-blinded, placebo-controlled study

I am however heartened by the outstanding ongoing contribution from people in the research community, patient advocacy groups and by patients themselves who are speaking up about their symptoms and treatment to raise awareness and campaign for better understanding and treatment.

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