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99 A placebo-controlled trial with 45 participants found 600 IU of dl-alpha-tocopherol (equivalent to about 300 IU of active d-alpha-tocopherol) per day and 40 mcg (1,600 IU) of vitamin D3 per day each reduced eczema symptoms more than placebo, but treatment with both vitamin E and vitamin D had an even greater positive effect

In addition, ATF3 (67, 68) and EGR2 (69, 70) play crucial roles in signal transduction in the process of anti-apoptosis, anti-migration, and anti-inflammation

10.1111/jcmm.15260 17 ChengA

The melanocytes were confirmed by Masson-Fontana silver stain [Figure - 4]
