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Surgical procedure The rats were tracheotomized, and a heparinized catheter was inserted into the femoral artery to record systolic (SBP) and diastolic (DBP) BP

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The structural similarity to insulin explains the ability of IGF-1 to bind (with low affinity) to the insulin receptor

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It produces nearly all blood proteins, except gamma globulins, and synthesizes a significant portion of amino acids

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HIM-2 A randomized, single-blind, placebo-controlled, three-way crossover dose-escalation study sponsored by Nobex Corporation studied the efficacy of HIM-2 on postprandial glucose levels in patients with T2DM, in addition to its safety profile

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