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Medical trials involving collaboration between clinicians, materials scientists, and pharmacologists will help define regulatory pathways and develop scalable manufacturing methods

The actual overall survival after enrollment was calculated using the Kaplan-Meier method and differences in the resulting distributions were compared by the log-rank test

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In addition, chemerin/CMKLR1 signaling can abrogate basal canonical Wnt signaling in SSCs by inducing PPAR-mediated ubiquitination of the central Wnt transducer, -catenin, which subsequently suppresses osteoblastogenesis and promotes adipogenesis (357)