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In addition, PI3K promotes mTORC2 activation [46]

Chem Sci Technol

Delayed and accelerated aging share common longevity assurance mechanisms

Recent studies show that metformin can alleviate age-associated inflammation by increasing autophagy and improving mitochondrial function, both of which are relevant biological features involved in PD-related cellular damage pattern (Jung et al., 2012), a mechanism that can protect pancreatic cell against lipotoxicity
