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In 2010 a multicentre randomised trial suggested that celiprolol decreased the incidence of arterial rupture or dissection in patients with a clinical diagnosis of vascular EDS

This article walks through what the before and after timeline actually looks like at 3, 6, and 12 months based on clinical observations from our patient population, what affects the magnitude of results, and who is the right candidate for this protocol

DSIP can often be safely combined with other sleep wellness approaches including cognitive behavioral therapy for insomnia (CBT-I), sleep hygiene optimization, other recovery-supporting peptides, magnesium and sleep-supporting supplements, melatonin (under medical guidance), adaptogenic herbs, and comprehensive sleep optimization protocols when properly coordinated under medical supervision
