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It was concluded that HA08 binds to IRAP in a very similar conformation to what was proposed by the MD simulations (Diwakarla et al., 2016b

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Research demonstrated that a seven-amino acid peptide corresponding to the actin-binding motif (LKKTETQ, the core of what would be identified as TB-500) could promote wound repair in aged animals at levels comparable to the full-length parent molecule