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Wang AJJ, Li CH, Li SD, Lin YF, Liu SJ (Inventor) Wang AJ, Jian SJ

Normally, Nrf2 is sequestered in the cytoplasm by Keap1 (Kelch-like ECH-associated protein 1), a protein that also acts as an adaptor protein for the Cullin 3-dependent E3 ubiquitin ligase to mediate the ubiquitination and degradation of Nrf2

This invaluable substance thus has remarkable liver-related detoxification properties and is responsible for eliminating many 'xenobiotic' (foreign) toxins