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Epigenetic alterations induced by hyperglycemia, including increased methylation at H4K20, acetylation at H3K9, and LSD1-mediated demethylation at H3K4, affect the promoter and enhancer regions of SOD2, resulting in its downregulation

In addition, myristic acid also affects the membrane translocation of Fyn kinase and the activation of Src family kinases, interfering with the expression or activity of coagulation-related factors, thereby affecting the coagulation process [52]

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Emerging roles for eicosanoids in renal diseases