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Diagnostic tests In general, diagnostic tests for food allergy (e.g., SPT, food-specific serum IgE, and OFCs) should be performed by an allergist

15 Both extrahepatic factorssuch as adipokine production, caloric and nutrient imbalance, and IRand intrahepatic mechanismsincluding impaired fatty acid oxidation, mitochondrial dysfunction, endoplasmic reticulum stress, oxidative stress, and activation of resident macrophagesdrive the onset of MAFLD and its progression to MASH
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Examples of such conditions include myeloproliferative disorders (e.g., chronic myelogenous leukemia, polycythemiavera), severe liver diseases, and alcoholism
