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Journal of the International Society of Sports Nutrition, 13, 29

In consequence, acylcarnitines constitute an appreciable component of the tissue carnitine pool, and tissue and plasma concentrations of carnitine and acylcarnitines are together maintained within relatively narrow limits by a variety of mechanisms, which influence in turn innumerable aspects of carbohydrate and lipid metabolism, including the regulation of insulin secretion by pancreatic -cells and the determination of tissue insulin sensitivity

Pharmacokinetics of L-carnitine in patients with end-stage renal disease undergoing long-term hemodialysis