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Antipsychotic medicines constituted the largest class of inhibitors among these 31 compounds, closely followed by general antiseptic agents (Butts et al., 2013)
doi: 10.1111/j.1753-4887.2004.tb00060.x
The CSNB mutant T94 2.61 I mutant is constitutively active 18,19 but does not show increased dark-state activity compared to the WT 16 , despite it results in extremely long-lived Meta II intermediate 14,18 E134 3.49 Q exhibits 1.5-fold dark-state activity relative to WT and is constitutively active 8,15
Some nootropics can also affect psychiatric problems
