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As the ROS levels are very low in FISCs from both Keap1 +/- and Keap1 -/- mice 25,30 (Supplementary Fig

MCT1 is responsible for both influx and efflux of lactate as well as for transport of lactate into the mitochondria and the peroxisomes

*Correspondence: Michael B

T2D is a multifactorial, complex disease and can be controlled by diet modifications, control of physical activity, weight reduction, etc
