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Beyond the general mechanisms of silybin, research on specific derivatives has revealed unique actions

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Disruption of any of these axes, including iron overload, PUFA enrichment, cysteine depletion, or selenium deficiency, can shift the cellular balance towards ferroptotic collapse

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One plausible explanation is that triglyceride synthesis serves to secure energy deposits, thus mitigating the risk of passive dependence on environmental nutrients, as discussed earlier

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