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Jiang et al., 2015), the role of iron load in this death signal is poorly resolved (Doll and Conrad, 2017)

Optional research biomarkers: senescence markers (p16^INK4a, SA--gal), SASP cytokine profile (IL-6, IL-1, MMPs) if lab resources permit

135,227,228,229,230 For instance, brahma-related gene 1 (BRG1) interacts with NF-B to activate eotaxin transcription, which induces eosinophil infiltration and the subsequent secretion of IL-4, that drive hepatocyte proliferation

Candidate SNP of CACNA2D1 gene associated with clinical mastitis and production traits in Sahiwal (Bos taurus indicus) and Karan fries (Bos taurus taurus Bos taurus indicus)
