glutathione binding site gst GSH and substrate sites of S-transferase genes. The RCSB PDB - 1GNW: STRUCTURE
Description
Evol 8, 827839
These neurotransmitters are synthesized from tryptophan and tyrosine via hydroxylation and decarboxylation, and are metabolized by monoamine oxidase (MAO)
In this process, glutathione forms a reversible mixed disulfide bond with the vulnerable cysteine residues of cellular proteins, effectively shielding them from permanent oxidative destruction
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