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No single therapy works for everyone
As such, the key proteins involved in the dialogue between CSCs and the TME merit deeper investigation as prospective therapeutic targets for future cancer treatments
Pirhaghi M, Frank SA, Alam P, Nielsen J, Sereikaite V, Gupta A, Stromgaard K, Andreasen M, Sharma D, Saboury AA, Otzen DE
Upon clinical examination of the cysteine-deficient mice, 30% weight loss is considered a moribund state that required euthanasia
