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2 Therapeutic effects of clemastine in animal models and potential molecular mechanisms Since being identified for potential repurposing, clemastine has been administered in various animal models associated with demyelination (Figure 1A)

10.1096/fj.201901474RR 8 DalleS.QuoyerJ.VarinE.CostesS

Glutathione is a potent antioxidant that fights the free radicals that can cause oxidative stress and damage healthy cells

As illustrated in Figure 3 , some researchers hypothesize that molecular mimicry between antigens of the SARS-CoV-2 virus and self-antigens in the thyroid gland could contribute to the development of autoimmune thyroid disorders, including GD, following COVID-19 vaccination