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SAMe is a methyl donor involved in various methylation reactions in the body, including the synthesis of some neurotransmitters, such as dopamine and serotonin
[DOI] [PMC free article] [PubMed] [Google Scholar] 2.Johnson ER, Matthay MA

For hair growth specifically, combining topical GHK-Cu with microneedling is supported by the strongest evidence as shown in the 2025 Kuceki study which achieved 26.5% regrowth with this combination approach

C., & Grundmann, O
