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In addition, 4-chloropyridine 10 and 4-chloronicotinamide 11 were reported to be suicide substrates as they can be N -methylated by NNMT and subsequently react with C159 to inactivate NNMT with k obs /[I] values of 20 M 1 min 1 and 80 M 1 min 1 , respectively

This will vary amongst people of different ages and circumstances

Other mild pain killers, such as paracetamol, may be effective for some patients, but may not be helpful for everybody

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