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A study evaluating different antioxidants found that, in controlled doses, glutathione reduces cell oxidation levels by up to 30% more than vitamin C and by 20% more than vitamin E after four weeks' use 1
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2018;97(45):e13087. N-Acetylcysteine for the Treatment of Psychiatric Disorders: A Review of Current EvidenceSoo Liang Ooi

For example, patients who are refractory to IMiDs have a higher frequency of cereblon mutations (210%) than untreated patients (0.5%)