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Of note, pharmacologically induced PFC NMDAR hypofunction leads to increased oscillations [99] while genetic deletion of NMDAR1 subunits in pyramidal neurons increases oscillations, cell excitability and sEPSC frequency [100], similar to the present data

Sequelae were generally slight in 12% of patients, mild in 13%, and severe only in 4% [4]

This emphasizes the potential therapeutic benefits of KD in neurodegenerative diseases [38]

6.3 Ferroptosis and autophagy Autophagy is the process of removing and degrading intracellular material through lysosomes, which includes macroautophagy, microautophagy, and chaperone-mediated autophagy