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[DOI] [PMC free article] [PubMed] [Google Scholar] 157.Mohammadi S., Ghaderi S

A significant proportion of APAP overdoses are known to be chronic in nature and/or associated with long-term exposure to APAP at doses above those recommended by the manufacturer (Daly et al

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Pharmacological strategies include medications for T2DM (GLP-1 receptor agonists, SGLT2 inhibitors, biguanides, thiazolidinediones), lipid-lowering drugs (statins, cholesterol absorption inhibitors), antihypertensive drugs, hepatoprotective agents (UDCA, FXR agonists), probiotics/prebiotics/synbiotics targeting the gut microbiota, PPAR agonists, thyroid hormone receptor agonists (THR- agonists), fibroblast growth factor analogs (FGF19/FGF21), and newly developed DNL inhibitors (ACC inhibitors, FAS inhibitors, SCD1 inhibitors, DGAT inhibitors, ketohexokinase inhibitors, MPC inhibitors), miRNAs, and nanoparticles as drug delivery systems