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John's wort, and increased ALT activity and hypoglycemia after accidental ingestion of high doses of -lipoic acid in two dogs.129, 131 The paucity of reported hepatic reactions does not necessarily mean herbal and dietary supplements are safe, and the clinician should maintain a high level of suspicion regarding their potential toxicity

The research was partially supported by a grant from the U.S

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Antioxid Redox Signal 23:11711185 Yumnamcha T, Devi TS, Singh LP (2019) Auranofin mediates mitochondrial dysregulation and inflammatory cell death in human retinal pigment epithelial cells: implications of retinal neurodegenerative diseases