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Myelodysplastic syndromes (MDS) MDS is a very heterogeneous group of myeloid clonal disorders characterized by ineffective hematopoiesis, peripheral blood cytopenia, and clonal instability with a tendency to progress into AML [516]

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Preparation of nuclear and cytosolic extracts and Nrf2 activity assay Nuclear and cytosolic extractions (310 5 cells) were prepared using the Active Motif Nuclear extraction kit (Active Motif, Carlsbad, Calif) according to the manufacturers instructions

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