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Colonoscopy, mammography, Pap smears, PSA testing, and skin examinations as appropriate for age and risk factors detect cancers early when treatment is most effective

[DOI] [PMC free article] [PubMed] [Google Scholar] 85.Seino Y., Fukushima M., Yabe D

Rats were assessed for fine motoric impairment with modified Irvine, Beatties and Bresnahan forelimb scale (IBB scale) that can detect recovery of both proximal and distal forelimb function including digit movements during a naturally occurring behavior that does not require extensive training or deprivation to enhance motivation (64)

An alternative is to develop substances that are safer for the epithelial barrier and are substitutes for commonly used, dangerous compounds [1]
