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This symptom is usually the result of anemia, which can be caused by a lack of B-12
This rhythm is maintained even after cholecystectomy, where the fraction of the bile acids stored in proximal intestine is increased but bile acid metabolism and enterohepatic cycling is largely intact
Furthermore, pharmaceutical agents, including metformin, curcumin, quercetin, and certain anti-inflammatory medications, can stimulate AMPK activity
