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Idiopathic pulmonary fibrosis--A disorder of alveolar wound repair

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For example, zinc is a crucial component of the SOD enzyme system, while lead is involved in the electron transport chain of ROS

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Since a succinyl-group transfer introduces a relatively large structural moiety (100 kDa) compared to lysine methylation and acetylation [16], it has been proposed that succinylation modification could induce a relatively large shift in the charge and the structural alteration with significant effects on the function of the target protein

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