glutathione free radical scavenger in french Biochemical functions associated with inside bacterial An in vitro study on
Description
-Glutamylcysteine ligase expression is subject to regulation by Nrf2, a transcription factor that regulates a wide array of antioxidant responsive element (ARE)-driven genes in various cell types, and thus plays a central role in cellular antioxidant defenses (Jaiswal, 2004
PLoS Negl Trop Dis 12(1):e0006096
The mRNA transcripts of the GCLC subunit of glutamate cysteine ligase, which is the rate-limiting enzyme in GSH biosynthesis, as well as SLC7A11 which encodes the cystine/glutamate antiporter xCT, are previously unidentified targets for the RIDD activity of IRE1
doi: 10.3390/genes13122380
