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23 The biological mechanisms underpinning weight lossmediated reductions in BP are well-established, with decreased body fat, notably visceral adipose tissue, associated with numerous antihypertensive effects, including a reduction in arterial stiffness, improved insulin sensitivity, and reduced inflammation

It doesn't necessarily kill all bacteria on contact (that would be bactericidal), but it creates an environment where they simply can't multiply

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To respond to the high and dynamic NAD + cellular demand for both redox and nonredox processes, mammalian cells must synthesize NAD + from different dietary precursors through the de novo pathway and the PreissHandler pathway (Fig