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Its effects can last several hours, which is why evening use is discouraged.
Dunham experienced a range of side-effects including nausea, migraines, and constipation, she said
Sources Endogenous biosynthesis R -lipoic acid is synthesized endogenously by humans (see Metabolism and Bioavailability)
Patients taking 800 mg of oral ALA daily for four months demonstrated significant improvements in resting heart rate variability, signaling a reversal or delay of autonomic nerve dysfunction
