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Reported side effects are usually mild and short-lived
Enzymatic polysorbate degradation may impair the functionality of the surfactant in stabilising therapeutic proteins, leading to the formation of visible and/or sub-visible particles in biopharmaceutical drug products
[PMC free article: PMC10765711] [PubMed: 38172996] 37
There is no prospective evidence above 2.4 mg weekly, so pushing higher is not a useful plateau strategy
