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Journal of Experimental Botany 74, 976990
Defects in regulatory T cells (Tregs) and increased expression of inflammasome components further amplify sensitivity to thyroid autoantigens
d , Top, percent cell number from SLC33A1 -knockout HEK293T cells expressing inducible ER-GshF (iER-GshF) complemented with a vector control, SLC33A1 or SLC33A1 MAP cDNA under indicated concentrations of doxycycline for 4 days
The recommended phase 2 dose (RP2D) for cabozantinib was 40 mg daily and the trial was expanded to a phase II multi-cohort, multi-center trial of 117 patients (Saeed et al., 2023)
