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Abnormalities of Homocysteine Metabolism Dysfunctions related to congenital defects in enzymes involved in homocysteine metabolism, to deficiencies in the supply, absorption, or metabolism of folates, vitamins B 12 and B 6 , and to dietary methionine excess all contribute to increasing plasma homocysteine levels (Table 1)

2007;178(1):338343 [DOI] [PMC free article] [PubMed] [Google Scholar] 28

W., Leslie, F

SS-31 directly targets the mitochondrial dysfunction that is a primary mechanism of taxane and platinum-based chemotherapy neurotoxicity
