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For example, when we take vitamin C by mouth the blood concentration tends to reach an upper limit due to GI absorption saturation and kidney clearance of the vitamin ( 1 )
NF-B within activated microglia also promotes inducible nitric oxide synthase (iNOS) that produces nitric oxide (NO) which in turn enhances S aggregation by impairing the ubiquitin-proteasome machinery (Tao et al., 2019)
