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How Modifier 59 Differs from Modifier 91 Unlike Modifier 91, which specifically indicates the repetition of a diagnostic test or procedure, Modifier 59 is used to indicate separate and distinct services

The prescribing information for Adderall XR states that, in general, stimulant medications can increase heart rate and cause an average increase in blood pressure of about 2 to 4 mmHg: Stimulant medications cause a modest increase in average blood pressure (about 2-4 mmHg) and average heart rate (about 3-6 bpm), and individuals may have larger increases