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It has been reported to inhibit -amylase and -glucosidase enzymes, inhibit gluconeogenesis, increase the translocation of GLUT4, increase glucose uptake in skeletal muscle, and reduce fatty acids, triglycerides, and cholesterol levels [555]

Following a similar approach, it was demonstrated that a decreased level of SFN results in neuroinflammation and oxidative stress, as indicated by lower concentrations of malondialdehyde, TNF- , and IL-1, respectively (85)

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doi:10.1021/acsinfecdis.0c00288 Ghezzi P, Lemley KV, Andrus JP, De Rosa SC, Holmgren A, Jones D, Jahoor F, Kopke R, Cotgreave I, Bottiglieri T, Kaplowitz N, Nakamura H, Staal F, Ela SW, Atkuri KR, Tirouvanziam R, Heydari K, Sahaf B, Zolopa A, Frye RE, Mantovani JJ, Herzenberg LA, Herzenberg LA