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In addition, there are species-specific differences in overall LXR responses that need to be carefully considered meaning the use of animal models that more closely resemble humans in their metabolic pathways
Studies have demonstrated that these medications improve outcomes, including decreased platelet aggregation, improved blood pressure, enhanced glycemic control, a reduced risk of major adverse cardiac events, and a decrease in the rate of renal dysfunction
Kidney function should be adequate, as carnitine metabolism relies on renal clearance
