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[DOI] [PMC free article] [PubMed] 272.Hong WL, Huang H, Zeng X, Duan CY

Hcy-thiolactone reacts with proteins by -linking to the -amino group of protein lysine residues (homocysteinylation), resulting in protein damage [5]

These toxic substances induce toxic neurological damage by disrupting cellular metabolism and signaling pathways, leading to oxidative stress and apoptosis

Response rates to anti-PD-1 immunotherapy in microsatellite-stable solid tumors with 10 or more mutations per megabase