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doi: 10.1111/j.0022-202X.2004.22516.x

Women who combined black seed supplements with a low-calorie diet lowered their cholesterol more than women who didnt take the supplements

Published by: The Nutritional Medicine Institute Open Access: This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs licence ( which permits non-commercial reproduction and distribution of the work, in any medium, provided the original work is not altered or transformed in any way, and that the work is properly cited

Joint discomfort associated with B12 supplementation is uncommon and not listed amongst the recognised adverse effects in the Summary of Product Characteristics (SmPC) for licensed B12 preparations or in the British National Formulary (BNF)
