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Association for Surgical Education Annual Meeting, Surgical Education Research Fellowship Workshop, 2012

meningitidis MC58 strain was shown to be internalized into the endothelial cells and to cross the barrier within 24 hours without disruption of junctional proteins or alteration in TEER, indicating a transcellular crossing ( Type IV pili interaction with CD147 on endothelial cells has also been demonstrated to induce an increase in sphingosine 1-phosphate receptor 2 (S1PR2) and the activation of the S1P-S1PR2-EGFR axis, leading to bacterial uptake (Maceyka et al., 2012)

Decreased protein expression levels (BMAL1, CLOCK and SIRT1) induced by FFA and their phase shift were also partially reversed by resveratrol

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