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This discrepancy in reports of LTCC dependence in LCAC-provoked Ca 2+ overload could be due to differences in LCAC and verapamil doses, as well as the myocardial preparation used (i.e., isolated myocyte vs

Group I (control) administered of corn oil, Group II administered LC (500 mg/kg/day), Group III administered BPA (100 mg/kg/day), Group IV administered BPA (300 mg/kg/day), Group V was co-treated with BPA (100 mg/kg/day) and LC , and Group VI administered co-treatment with BPA (300 mg/kg/day) and L-carnitine

This phase can be as short as 21 days or as long as 80 days