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First, its role as a collagen synthesis co-factor directly supports the production and maintenance of the dermal collagen that gives skin its firmness, elasticity and structural quality

[ 408 , 409 ] BACH1 deficiency inhibits alloxaninduced reduction in pancreatic insulin content and the resulting glucose elevation by reducing the apoptosis of pancreatic cells under oxidative stress

Chronic stress in a rat model of depression disturbs the glutamine-glutamate-GABA cycle in the striatum, Hippocampus, and cerebellum

In preclinical and clinical studies, it has shown superior in vitro activity and consistent therapeutic effects in animal models