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Another study showed that administration of silibinin with ionizing radiation inhibited the proliferation of the endothelial cell as well as reduced the migratory and invasive properties of prostate cancer cells (70)
Future studies employing chromatin immunoprecipitation assays will be necessary to definitively test whether HIF-1 and/or c-Myc directly bind to the SLC16A1 promoter in SCs and how this is governed by SYK activity
10.1021/am5025897
