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In diet-induced obese mice (16 weeks HFD), subcutaneous 5-Amino-1MQ treatment for 11 days (20 mg/kg/injection, three injections daily) produced significantly reduced body weights, white adipose tissue masses, and adipocyte cell sizes compared to vehicle controls

Such a significant reduction in iron release could conceivably diminish both inflammation and oxidative stress, the latter being a condition where damaging oxidative processes occur more rapidly than the body's ability to counteract them, in the affected tissues

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DemeuleMRginaAJodoinJLaplanteADagenaisCBertheletFet alDrug transport to the brain: key roles for the efflux pump P-glycoprotein in the blood -brain barrier
