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Research suggests that increased autophagy and proteasomal activity in the heart may possibly be cleared by FOXO signaling

The development and maintenance of paclitaxel-induced neuropathic pain require activation of the sphingosine 1-phosphate receptor subtype 1

Fin56-induced ferroptosis is supported by autophagy-mediated GPX4 degradation and functions synergistically with mTOR inhibition to kill bladder cancer cells

Discussion In the present study, we confirm that Gsdmd cKO in SCs largely reduced the threshold elevation and OHC loss caused by noise exposure (2 h, 100 dB SPL), while no protection effect was observed in Gsdmd -HC-cKO mice