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This causes an uncoordinated release of interferon-gamma and interleukin-2, precipitating sudden and profound hemodynamic collapse

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It is noteworthy that when patients were recruited to this study, in July 2020, vaccines were not yet available and dexamethasone and other glucocorticoids had recently been integrated to the COVID-19 therapeutic protocol

Wei R, Song J, Liu X, Huo S, Liu C, Liu X