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Description
Although both dysregulated hepatic glutathione homeostasis and TNF overproduction are critically involved in the development of NAFLD, whether they can be synergistically implicated in hepatocyte death remains to be clearly defined

C., Hagiwara, A., Han, J., & Lee, J

[DOI] [PubMed] [Google Scholar] 69.Healy C.R., Gethin G., Pandit A., Finn D.P

Following TNF binding to TNFR1, a cascade leads to the formation of complex I, which includes TNF-receptor-associated death domain protein, TNF-receptor-associated factor 2, cellular inhibitor of apoptosis protein 1 or 2 and the linear ubiquitin chain assembly complex
